Product Description:
4-Androstenedione 4-AD
CAS No: 63-05-8
Molecular Formula: C19H26O2
Molecular Weight: 286.41
Molecular Structure:
Packing: 5kg (aluminum cans)
Specification: 99% Heavy 10PPM Rotation +193 ¡ã - +202 ¡ã Loss on drying 0.5% impurity 1% steroid hormone
Characters: near white crystalline powder, soluble in ethanol, insoluble in water
Uses: Simplified hormone drugs, from the testis or urine extracted with the role of a male hormone steroids, norethisterone, testosterone propionate in the middle
Body, is widely used in small rheumatoid arthritis, diuretic, and a variety of contraceptive to control infectious inflammation.
Benefits:
Some body builders report anecdotally that they notice increased strength on the days they work out when they use it. Others use it occasionally to boost sex drive or wellbeing. Those who are young and already have high levels of testosterone or androstenedione in their system are not likely to notice much of a sex boosting effect. Middle aged and older individuals may notice the benefits more easily. It is potentially an alternative to DHEA or testosterone as a form of androgen replacement in aging men or women.
A highly publicized study indicates that androstenedione may not live up to its hype. The study published in the June 2, 1999 issue of the Journal of the American Medical Association compared 300 mg with a dummy pill in 20 men ages 19 to 29 during an eight-week weightlifting program. Researchers found no difference in strength between the two groups of men.
Applications:
Androstenedione is the common precursor of male and female sex hormones. Some androstenedione is also secreted into the plasma, and may be converted in peripheral tissues to testosterone and estrogens.
Androstenedione can be synthesized in one of two ways. The primary pathway involves conversion of 17-hydroxypregnenolone to dehydroepiandrosterone by way of 17,20-lyase, with subsequent conversion ofdehydroepiandrosterone to androstenedione via the enzyme 3-hydroxysteroid dehydrogenase. The secondary pathway involves conversion of 17-hydroxyprogesterone, most often a precursor to cortisol, to androstenedione directly by way of 17,20-lyase. Thus, 17,20-lyase is required for the synthesis of androstenedione, whether immediately or one step removed.
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